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Satan commissions Demonyita to destroy the souls of four young good-looking men, but San Pedro from heaven also sends an angel to thwart Satan's plans. Demonyita succeeds in creating havoc in the lives of these men. But when Daniel, one of the four, really falls for her, things turn out differently as he sets out to exorcise the "devil" out of her.

Trixie (Francine) has definite dreams; to be a wife to the man she loves... Tony (Christian Vasquez) is the man in Trixie's life and still feels passionate about his ex-love Pauline. Pauline is bohemian and lives life to the fullest... Katrina (Tuesday Vargas) received her first love letter at 16, and got pregnant... Frankie (Rodel Velayo) is and will always be gay... Society's norms are questioned and put to test by these five friends.

Cristy is a gambler in too deep with debt from Facundo and Aurora. When she finds out that her debtor's son has taken a liking for her daughter, Susie, Cristy devices a scheme to get rid of her debts by committing Susie's hand in marriage with her debtor's son.